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Brilliant Minds/Once Upon a Time in America
| Once Upon a Time in America | |
| Season 2, Episode 5 | |
| Airdate | October 20, 2025 |
| Production Number | T13.26205 |
| Written by | Stasia Demick & Shannon Looney |
| Directed by | Paris Barclay |
| ← 2x04 Lady Liberty |
2x06 → The Doctor's Graveyard |
| Brilliant Minds — Season Two | |
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Once Upon a Time in America is the fifth episode of the second season of Brilliant Minds, and the eighteenth episode overall.
Starring: Zachary Quinto (Dr. Oliver Wolf), Tamberla Perry (Dr. Carol Pierce), Ashleigh LaThrop (Dr. Ericka Kinney), Aury Krebs (Dr. Dana Dang), Teddy Sears (Dr. Josh Nichols), John Clarence Stewart (Dr. Anthony Thorne), Al Calderon (Nurse Scotty Silva)
Guest Starring: Spence Moore II (Dr. Jacob Nash), Joshua De Jesus (Benny Torres), Joshua Diaz (Jorge Torres), Sol Miranda (Ana Torres), Kiki Hammill (Maya Allen)
Co-Starring: Nayeli Abrego (Pilar), Madison Brydges (Sasha), Ric Garcia (Uncle Luis), Oren N. Gottfried (Neurological Fellow #2), Anna Hopkins (Davie), Andi E McQueen (Medic), Kyle O'Neill (Scrub Tech), Jenny Raven (Dr. Mia Clark), Dorrett White (Nurse Estelle Carter)
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