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Negative Reaction is the second episode of the fourth season of Columbo, and the twenty-seventh episode overall.
Guest Stars: Dick Van Dyke (Paul Galesco), Don Gordon (Alvin Deschler), Larry Storch (Mr. Weekly), Antoinette Bower (Frances Galesco), Joyce Van Patten (Sister of Mercy), David Sheiner (Ray), Michael Strong (Sgt. Hoffman)
with Alice Backes (Mrs. Moyland), Harvey Gold (Harry Lewis), Bill Zuckert (Capt. Sampson), Adrian Ricard (DMV Clerk), Thom Carney (Manager), Tom Signorelli (Doctor), John Ashton (Calvin MacGruder), Edward Colmans (Minister), Irene Tedrow (Mrs. Charleswort), Mike Santiago (1st Policeman), Edward Cross (2nd Policeman)
A photographer claims that he shot the man who killed his wife in self-defense, but Columbo finds holes in his story.