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Lockdown is the twenty-second episode of the eighth season of ER, and the one hundred seventy-ninth episode overall.
Starring: Anthony Edwards (Dr. Mark Greene) (credit only), Noah Wyle (Dr. John Carter), Laura Innes (Dr. Kerry Weaver), Alex Kingston (Dr. Elizabeth Corday) (credit only), Paul McCrane (Dr. Robert Romano), Goran Visnjic (Dr. Luka Kovac), Maura Tierney (Nurse Abby Lockhart), Sherry Stringfield (Dr. Susan Lewis), Ming-Na (Dr. Jing-Mei Chen), Sharif Atkins (Dr. Michael Gallant)
Guest Starring: Paul Hipp (Craig Turner), Alison La Placa (Female Lawyer), Abraham Benrubi (Jerry Markovic), Deezer D. (Malik McGrath), Yvette Freeman (Haleh Adams), Lily Mariye (Lily Jarvik), Monté Russell (Zadro), Christopher Birt (), Larry Clarke (Male Lawyer), Kingston DuCoeur (), Dee Freeman (Dr. Lutz), Marjorie Lovett (Marge Satterfield), Harrison Page (Stan), Curtis Peek (), Nestor Serrano (David Torres), Heidi Swedberg (Robin Turner), Jayne Taini ()
Co-Starring: Ken Abraham (Sean), Frankie Jay Allison (Frankie), Michelle C. Bonilla (Harms), Art Frankel (Ralph Meyers), Dee Anne Helsel (Deanne), Miranda Kwok (Kristen), Alice Lo (Lenore Fong), Charles Martiniz (Eddy), John C. McDonnell (Rick), Kristy Munden (TV Anchor), Lisa Picotte (Pregnant Woman), Raoul Rizik (Raoul), Bella Shaw (Robinson), Scott St. James (Drasnin), Isidra Vega (Marta Guzman), Sean Virzi (Adam (1)), Alex Virzi (Adam (2)), Mitchell Virzi (Adam (3)), Emily Wagner (Pickman)
Carter and Abby tend to two kids who exhibit signs of smallpox which causes the ER to be placed under lockdown; Chen and Pratt are placed in quarantine with a homeless man named Stan when they begin developing symptoms; the ER has their hands filled with senior citizens injured in a bus accident and disgruntled patients who demand to know why they can't leave the ER which ends up causing a riot.