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Grey's Anatomy/Goodbye Horses

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Goodbye Horses
Season 22, Episode 4
Airdate October 30, 2025
Written by Jase Miles-Perez
Directed by Sammi Cannold
← 22x03
Between Two Lungs
22x05 →
Sometimes I Feel Like a Motherless Child
Grey's AnatomySeason Twenty-Two
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Goodbye Horses is the fourth episode of the twenty-second season of Grey's Anatomy, and the four hundred fifty-second episode overall.

Starring: Ellen Pompeo (Dr. Meredith Grey), Chandra Wilson (Dr. Miranda Bailey), James Pickens, Jr. (Dr. Richard Webber), Kevin McKidd (Dr. Owen Hunt), Caterina Scorsone (Dr. Amelia Shepherd) (credit only), Camilla Luddington (Dr. Jo Karev) (credit only), Jason George (Dr. Ben Warren), Kim Raver (Dr. Teddy Altman), Chris Carmack (Dr. Atticus Lincoln), Anthony Hill (Dr. Winston Ndugu), Alexis Floyd (Dr. Simone Griffin), Harry Shum Jr. (Dr. Daniel "Blue" Kwan), Adelaide Kane (Dr. Jules Millin), Niko Terho (Dr. Lucas Adams), Trevor Jackson (Dr. Wes Bryant) (credit only)

Guest Starring: Jesse Williams (Dr. Jackson Avery), Sophia Bush (Dr. Cass Beckman), Floriana Lima (Nora Young), Samantha Marie Ware (Katie Rogers), Anita Kalathara (Dr. Kavita Mohanty), Beth Malone (Perry Onikul), Manny Magnus (Vince), Raphael Alejandro (Jonah Nolan)

Co-Starring: Fran Nichols (Nurse Karen), Anton Starkman (Harrison Meade)

Contents

Plot Overview

Notes

Arc Advancement

Happenings

Characters

Referbacks

Trivia

The Show

Behind the Scenes

Allusions and References

Memorable Moments

Quotes