House, M.D./James Wilson

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James Wilson
House, M.D.
Actor Robert Sean Leonard
First Appearance 1x01 Pilot
Last Appearance
Series Billing Series: Billed
Episode Count 22 (through season 1)
Notable Episodes


Basic Information

James Wilson is the "boy wonder" Head of Oncology at Princeton Plainsboro Hospital, as well as House's best (and only) friend.

Character History

Memorable Moments


  • Wilson has been divorced twice. He cheated on his two ex-wives and it can be assumed that he is doing the same with his current wife.
  • He is a member of the hospital's transplant board.


Wilson: "I forgot, I need a reason to give a crap." House: "You're giving two craps." Wilson: "The metric system always confuses me." Episode: Histories

House: "Cameron sees a clump of dirt and she thinks of me." Dr. Wilson: "Or a lump of something else." Episode: Que Sera Sera