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Missing is the ninth episode of the tenth season of ER, and the two hundred tenth episode overall.
Starring: Noah Wyle (Dr. John Carter) (credit only), Maura Tierney (Nurse Abby Lockhart), Mekhi Phifer (Dr. Gregory Pratt), Alex Kingston (Dr. Elizabeth Corday), Goran Visnjic (Dr. Luka Kovac), Sherry Stringfield (Dr. Susan Lewis), Ming-Na (Dr. Jing-Mei Chen) (credit only), Sharif Atkins (Dr. Michael Gallant), Parminder Nagra (Dr. Neela Rasgotra), Linda Cardellini (Nurse Samantha Taggart)
Guest Starring: Daniel Dae Kim (Ken Sung), Troy Evans (Frank), Yvette Freeman (Haleh Adams), Shannon Lucio (Johanna Lambright), Wendy Phillips (Mrs. Lambright), John Eric Bentley (Larry Anderson), Niecy Nash (Judith Anderson), Michael Peña (Police Officer), Kyle Richards (Dori), Rossif Sutherland (Lester), Finn Wittrock (Thomas Yoder)
Special Guest Star: Joy Bryant (Valerie Gallant)
Co-Starring: Michelle C. Bonilla (Harms), Oliver Davis (Alex), Kevin Gonzalez (Nate), Brian Lester (Dumar), Danielle Lewis-Kates (Girl), Wayne Lopez (Benitez), Patrick Pankhurst (Dr. York), Terry Savage (Radiologist Nurse), Steve Seagren (Zimmer), Nick Vallelonga (Kohler), Emily Wagner (Pickman), Ruth Zalduondo (Radiologist), Karla Zamudio (Alma)
Neela treats two Amish teenagers who were injured during a trip to the city; Abby treats a little girl who is missing; Sam's son, Alex steals a severed finger from a patient and later runs away from home to County General to see Luka; Gallant's sister, Valerie comes to town and attracts Pratt's interest; Romano's memorial service is held at the hospital, but Corday is the only one who attends it.