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The Big Bang Theory/The Positive Negative Reaction
From The TV IV
| The Positive Negative Reaction | |
| Season 9, Episode 16 | |
| Airdate | February 18, 2016 |
| Production Number | 4X7216 / T12.15216 |
| Teleplay by | Steven Molaro & Steve Holland & Maria Ferrari |
| Story by | Eric Kaplan & Jim Reynolds & Saladin K. Patterson |
| Directed by | Mark Cendrowski |
| Stream |  |
| ← 9x15 The Valentino Submergence |
9x17 → The Celebration Experimentation |
| The Big Bang Theory — Season Nine | |
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The Positive Negative Reaction is the sixteenth episode of the ninth season of The Big Bang Theory, and the one hundred ninety-ninth episode overall.
Starring: Johnny Galecki (Dr. Leonard Hofstadter), Jim Parsons (Dr. Sheldon Cooper), Kaley Cuoco (Penny Hofstadter), Simon Helberg (Howard Wolowitz), Kunal Nayyar (Dr. Rajesh "Raj" Koothrappali), Mayim Bialik (Dr. Amy Farrah Fowler), Melissa Rauch (Dr. Bernadette Rostenkowski-Wolowitz)
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